About Us
About Us
  • Board Of Directors
  • Collaborators
  • Staff Directory
  • Job Openings
Our Legacy
Our Legacy
  • Achievements
  • History
  • Irene Diamond
  • Photo Gallery
Current Research
Current Research
  • Our Scientists and Labs
    • Paul Bieniasz
    • Cecilia Cheng-Mayer
    • Theodora Hatziioannou
    • David D. Ho
    • Yaoxing Huang
    • Martin Markowitz
    • Moriya Tsuji
  • Core Facilities
    • Personnel
    • Flow Cytometry
    • Microscope Imaging Facility
Clinical Trials
Clinical Trials
  • HIV+
    • Newly Infected With HIV
    • Living With HIV
    • Physicians
    • FAQ's
  • HIV.
    • Healthy Volunteer
    • FAQ's
Focus On HIV
Focus On HIV
  • Facts About HIV and AIDS
  • HIV Biology
    • The HIV Virus Particle
    • The HIV Replication Cycle
Giving Center
Giving Center
  • Online Giving
  • Other Giving Opportunities
  • Financial Summary
News Center
News Center
  • ADARC In The News
  • Seminars
  • Newsletters and Brochures
  • For Journalists
China Aids Initiative
China Aids Initiative
Multimedia Library
Multimedia Library
Talks at ADARC
Talks at ADARC
ADARC Gala
ADARC Gala
  • Gala video
  • Gala photo
  • leadership committee
  • Online Giving
Register for Updates
Register for Updates
Focus On HIV

HIV Biology


HIV enters the body through blood, semen or vaginal fluid. The virus cannot replicate on its own; instead, it seeks out cells so that it can replicate in them as an intracellular parasite. The CD4 T-cell is one of the more common cells that HIV virus particles seek out. A CD4 T-cell is a white blood cell (or lymphocyte). It is an essential part of the immune system that fights against foreign organisms in the body. By entering and replicating in a CD4 T-cell, the HIV virion ultimately destroys that cell. Because HIV replicates quickly and destroys many T-cells, HIV weakens the body’s immune system, making people with the virus more susceptible to additional infections.

Learn more about: