Research Labs: Cecilia Cheng-Mayer, Ph.D.
Selected Publications

Scientific Overview Non-Scientific Summary Cecilia Cheng-Mayer, Ph.D.    CV    Publications Return to Research Programs

1. Harouse, J.M., Gettie, A., Tan, R.C.H., Blanchard, J., and Cheng-Mayer, C. (1999) Distinct pathogenic sequela in rhesus macaques infected with CCR5 or CXCR4 utilizing SHIVs. Science 284:816-9. [view]
   
2. Brown, A., Wang, X., Sawai, E. and Cheng-Mayer, C. (1999) Activation of the PAK-related kinase by HIV-1 Nef in primary human peripheral blood lymphocytes and macrophages leads to phosphorylation of a PIX/p95 complex. J. Virol. 73:9899-907. [view]
   
3. Stamatatos, L., Lim, M. and Cheng-Mayer, C. (2000) Generation and structural analysis of soluble oligomeric envelope proteins derived from neutralization-resistant and neutralization-susceptible primary HIV-1 isolates. AIDS Res. Hum. Retro. 16: 981-94. [view]
   
4. Malenbaum, S., Yang, D., Cavacini, L., Posner, M., Robinson, J. and Cheng-Mayer, C. (2000) The N-terminal V3 loop glycan modulates the interaction of clades A and B HIV-1 envelopes with CD4 and chemokine receptors. J. Virol. 74:11008-16. [view]
   
5. Harouse, J.M., Gettie, A., Eshetu, T., Tan, R.C.H., Bohm, R., Blanchard, J., Baskin, G. and Cheng-Mayer, C. (2001) Mucosal transmission and induction of simian AIDS by CCR5-specific SHIVSF162P3: relevance for vaccine development. J. Virol. 75:1990-5. [view]
   
6. Harouse JM, Gettie A, Tan RC, Eshetu T, Ratterree M, Blanchard J, Cheng-Mayer C. (2001) Pathogenic determinants of the mucosally transmissible CXCR4-specific SHIV(SF33A2) map to env region. J Acquir Immune Defic Syndr. Jul 1;27(3):222-8. [view]
   
7. Malenbaum, S., Yang, D. and Cheng-Mayer, C. (2001) Evidence for similar recognition of the conserved neutralization epitopes of HIV-1 gp120 in humans and macaques. J. Virol., 75(19):9287-96. [view]
   
8. Chakrabarti LA, Metzner KJ, Ivanovic T, Cheng H, Louis-Virelizier J, Connor RI, Cheng-Mayer C. A truncated form of Nef selected during pathogenic reversion of simian immunodeficiency virus SIVmac239Deltanef increases viral replication. J Virol. 2003 Jan;77(2):1245-56. [view]
   
9. Hsu M, Zhang J, Flint M, Logvinoff C, Cheng-Mayer C, Rice CM, McKeating JA. (2003) Hepatitis C virus glycoproteins mediate pH-dependent cell entry of pseudotyped retroviral particles. Proc Natl Acad Sci U S A. 2003 Jun 10;100(12):7271-6. [view]
   
10. Harouse JM, Buckner C, Gettie A, Fuller R, Bohm R, Blanchard J, Cheng-Mayer C. (2003) CD8+ T cell-mediated CXC chemokine receptor 4-simian/human immunodeficiency virus suppression in dually infected rhesus macaques. Proc Natl Acad Sci. 100(19):10977-82. [view]
    
11. Reyes RA, Canfield DR, Esser U, Adamson LA, Brown CR, Cheng-Mayer C, Gardner MB, Harouse JM, Luciw PA. (2004) Induction of simian AIDS in infant rhesus macaques infected with CCR5- or CXCR4-utilizing simian-human immunodeficiency viruses is associated with distinct lesions of the thymus. J Virol. 78(4):2121-30. [view]
    
12. Brown A, Moghaddam S, Kawano T, Cheng-Mayer C. (2004) Multiple human immunodeficiency virus type 1 Nef functions contribute to efficient replication in primary human macrophages. J Gen. Virol. 85(6):1463-9. [view]
    
13. Balfe P, Shapiro S, Hsu M, Buckner C, Harouse JM, Cheng-Mayer C.. (2004) Expansion of quasispecies diversity but no evidence for adaptive evolution of SHIV during rapid serial transfers among seronegative macaques. Virology. 318(1):267-79. [view]
    
14. Brown, A., Moghaddam, S., Kawano, T. and Cheng-Mayer, C. (2004) Multiple human immunodeficiency virus type 1 Nef functions contribute to efficient replication in primary human macrophages. J. Gen. Virol.:85: 1463-9. [view]
    
15. Cheng, H., Cenciarelli, C., Nelkin, G., Tsan, R., Cheng-Mayer, C. and Fidler, I.J. (2005) Molecular mechanisms of hTid-1, the human homologue of Drosophila tumor suppressor (l2) Tid, in the regulation of NF-B activity and suppression of tumor growth. Mol Cell Biol 25: 44-59.[view]
    
16. Saunders, C.J., McCaffrey, R.A., Zharkikh, I., Kraft, Z., Malenbaum, S., Burke, B., Cheng-Mayer, C. and Stamatatos, L. (2005) The V1, V2 and V3 regions of the HIV-1 envelope differentially affect the viral phenotype in an isolate-dependent manner. J. Virol. 79: 9069-80. [view]
    
17. Brown, A., Gartner, S., Kawano, T., Benoit, N. and Cheng-Mayer, C. (2005) HLA-A2 down-regulation on primary human macrophages infected with an M-tropic EGFP-Tagged HIV-1 reporter virus. J. Leuk. Biol. 78: 675-85. [view]
    
18. Ho, S.-H., Shek, L., Gettie, A., Blanchard, J. and Cheng-Mayer, C. (2005) V3 loop determined coreceptor preference dictates the dynamics of CD4+ T cell loss in SHIV infected macaques. J. Virol. 79: 12296-303. [view]
    
19. Ratterree, M., Gettie, A., Williams, V., Malenbaum, S., Neurath, R.A., Cheng-Mayer, C. and Blanchard, J. (2005) Safety and distribution of cellulose acetate 1,2-benzenedicarboxylate (CAP), a candidate anti-HIV microbicide in rhesus macaques. AIDS 19: 1595-9. [view]
    
20. Boadi, T., Schneider, E., Chung, S., Tsai, L., Gettie, A., Ratterree, M., Blanchard, J., Neurath, R.A. and Cheng-Mayer, C. (2005) Cellulose acetate 1,2-benzenedicarboxylate protects against challenge with pathogenic X4 and R5 simian-human immunodeficiency viruses. AIDS 19: 1587-94. [view]
    
21. Hsu, M., Ho, S.-H., Balfe, P., Gettie, A., Harouse, J., Blanchard, J. and Cheng-Mayer, C. (2005) A CCR5-tropic simian-immunodeficiency virus molecular clone that is pathogenic in rhesus macaques. J Acquir Immune Defic Syndr. 2005 Dec 1;40(4):383-7. [view]
    
22. Ho SH, Shek L, Gettie A, Blanchard J and Cheng-Mayer C. 2005. V3 loop-determined coreceptor preference dictates the dynamics of CD4+-T-cell loss in simian-human immunodeficiency virus-infected macaques. J Virol, 79:12296-303. [view]
    
23. Boadi T, Schneider E, Chung S, Tsai L, Gettie A, Ratterree M, Blanchard J, Neurath AR and Cheng-Mayer C. 2005. Cellulose acetate 1,2-benzenedicarboxylate protects against challenge with pathogenic X4 and R5 simian/human immunodeficiency virus. AIDS 19:1587-94. [view]
    
24. Trunova N, Tsai L, Tung S, Schneider E, Harouse J, Gettie A, Simon V, Blanchard J and Cheng-Mayer C. 2006. Progestin-based contraceptive suppresses cellular immune responses in SHIV-infected rhesus macaques. Virology, 352:169-77. [view]
    
25. Ho SH, Martin F, Higginbottom A, Partridge LJ, Parthasarathy V, Moseley GW, Lopez P, Cheng-Mayer C and Monk PN. 2006. Recombinant extracellular domains of tetraspanin proteins are potent inhibitors of the infection of macrophages by human immunodeficiency virus type 1. J Virol 80:6487-96. [view]
    
26. Tsai L, Trunova N, Gettie A, Mohri H, Bohm R, Saifuddin M, Cheng-Mayer C. 2007. Efficient repeated low-dose intravaginal infection with X4 and R5 SHIVs in rhesus macaque: Implications for HIV-1 transmissions in humans. Virology, [view]
    
27. Tasca S, Tsai L, Trunova N, Gettie A, Saifuddin M, Bohm R, Chakrabarti L, Cheng-Mayer C. 2007. Induction of potent local cellular immunity with low dose X4 SHIVSF33A vaginal exposure: correlations with protection from re-exposure. [view]
    
28. Ho SH, Shek L, Li A, Gettie A, Blanchard J, Boden D, Cheng-Mayer C. 2007. Coreceptor switch in R5 SHIV infected macaque. Virology, 2007 May 30. [view]