Research Labs: Theodora Hatziioannou , Ph.D.
Curriculum Vitae

Scientific Overview Non-Scientific Summary Theodora Hatziioannou:    CV    Personnel    Publications Return to Research Programs

NAME: Theodora Hatziioannou

POSITION TITLE: Assistant Professor/Staff Investigator

EDUCATION/TRAINING

Positions and Employment

Other assignments

PUBLICATIONS

1. Boshoff C, Whitby D, Hatziioannou T, Fisher C, van der Walt J, Hatzakis A, Weiss RA, and Schulz TF.  1995.  Kaposi's-sarcoma associated herpesvirus in HIV-negative Kaposi's sarcoma.  Lancet, 345:1043-1044
   
2. Whitby D, Howard MR, Tenant-Flowers M, Brink NS, Copas A, Boshoff C, Hatzioannou T, Suggett FEA, Aldam DM, Denton AS, Miller RF, Weller IVD, Weiss RA, Tedder RS, and Schulz TF.  1995.   Detection of Kaposi's Sarcoma associated herpesvirus (KSHV) in peripheral blood of HIV-infected individuals predicts progression to Kaposi's sarcoma.  Lancet, 346:799-802.
   
3. Valsesia-Wittmann S, Morling FJ, Hatziioannou T, Russell SJ, and Cosset F-L. 1997.  Receptor co-operation in retrovirus entry: recruitment of an auxiliary entry mechanism after retargeted binding.  EMBO J, 16:1214-1223
   
4. Hatziioannou T, Valsesia-Wittmann S, Russell SJ, and Cosset F-L. 1998.  Incorporation of Fowl Plague Virus hemagglutinin into Murine Leukemia Virus particles and analysis of the infectivity of the pseudotyped retroviruses.   J Virol, 72:5313-5317.
   
5. Hatziioannou T, Delahaye E, Martin F, Russell SJ, and Cosset F-L. 1999.  Retroviral display of functional binding domains fused to the amino terminus of influenza hemagglutinin.  Hum Gen Ther, 10:1533-1544.
   
6. Hatziioannou T, Russell SJ, and Cosset F-L. 2000.  Incorporation of simian virus 5 fusion protein into MLV particles and its effect on the co-incorporation of retroviral glycoproteins.  Virology, 267:49-57.
   
7. Hatziioannou  T and Goff SP. 2001.  Infection of non-dividing cells by Rous sarcoma virus.  J Virol, 75:9526-9571.
   
8. Zhang Y, Hatziioannou T, Zang T, Braaten D, Luban J, Goff SP, and Bieniasz PD.  2002.  Envelope-dependent, cyclophilin-independent effects of glycosaminoglycans on human immunodeficiency virus type 1 attachment and infection.  J Virol, 76:6332-6343.
   
9. Cowan S, Hatziioannou T, Cunningham T, Muesing MA, Gottlinger HG, and Bieniasz PD.  2002. Cellular inhibitors with Fv1-like activity restrict human and simian immunodeficiency virus tropism.  Proc Natl Acad Sci, 99:11914-11919.
   
10. Hatziioannou T, Cowan S, Goff SP, Bieniasz PD, and Towers G.  2003.  Restriction of multiple divergent retroviruses by Lv1 and Ref1.  EMBO J, 22:385-394.
    
11. Towers GJ, Hatziioannou T, Cowan S, Goff SP, Luban J, Bieniasz PD.  2003.  Cyclophilin A modulates the sensitivity of HIV-1 to host restriction factors.  Nat Med, 1138-43.
    
12. Hatziioannou T, Cowan S, Bieniasz PD.  2004.  Capsid-dependent and –independent postentry restriction of primate lentivirus tropism in rodent cells.  J Virol, 78:1006-11.
    
13. Hatziioannou T, Cowan S, von Schwedler UK, Sundquist WI and Bieniasz PD.  2004.  Species-specific tropism determinants in HIV-1 capsid. J Virol. 78(11):6005-12.
    
14. Hatziioannou T, Perez-Caballero D, Yang A, Cowan S, Bieniasz PD.2004. Retrovirus resistance factors Ref1 and Lv1 are species-specific variants of TRIM5alpha. Proc Natl Acad Sci,20;101(29):10774-9.
    
15. Perez-Caballero D, Hatziioannou T, Martin-Serrano J, Bieniasz PD.  2004.  HIV-1 matrix inhibits and confers cooperativity on Gag precursor : membrane interactions. J Virol, 78(17):9560-3.
    
16. Hatziioannou T, David Perez-Caballero, Simone Cowan and Paul D. Bieniasz. 2005. Cyclophilin A interacts with incoming HIV-1 capsids with opposing effects on infectivity. J Virol, 79(1):176-183.
    
17. Perez-Caballero D, Hatziioannou T, Yang A, Cowan S and Bieniasz PD. 2005. Human tripartite motif 5alpha domains responsible for retrovirus restriction activity and specificity. J Virol, 79:8969-8978.
    
18. Naghavi MH, Hatziioannou T, Gao G and Goff SP. 2005. Overexpression of fasciculation and elongation protein zeta-1 (FEZ1) induces a post-entry block to retroviruses in cultured cells. Genes Dev,19:1105-1115.
    
19. Perez-Caballero D, Hatziioannou T, Zhang F, Cowan S and Bieniasz PD. 2005. Restriction of Human Immunodeficiency Virus Type 1 by TRIM-CypA Occurs with Rapid Kinetics and Independently of Cytoplasmic Bodies, Ubiquitin, and Proteasome Activity. J Virol, 79:15567-15572.
    
20. Hatziioannou T, Martin-Serrano J, Zang T and Bieniasz PD. 2005. Matrix-induced inhibition of membrane binding contributes to human immunodeficiency virus type 1 particle assembly defects in murine cells. J Virol, 79:15586-15589.
    
21. Zhang FW, Hatziioannou T, Perez-Caballero D, Derse D and Bieniasz PD. 2006. Antiretroviral potential of human Tripartite-motif-5 and related proteins. Virology,  353: 396-409
    
22. Hatziioannou T andBieniasz PD. Host resistance to retroviruses. Encyclopedia of  Virology, in press.
    
23. Hatziioannou T,Princiotta  M, Piatak M, Yuan F, Zhang F, LifsoN JD andBieniasz PD. 2006. Simian-tropic HIV-1 generated by restriction factor evasion.  Science, 314: 95.
    
24. Naghavi MH, Valente S, Hatziioannou T, de los Santos K, Wen Y, Mott C, Gundersen GG and Goff SP. 2007. Moesin regulates stable microtubule formation and limits retroviral infection in cultured cells. EMBO, 26: 41-52.
    
25. Evans MJ, von Hahn T, Tscherne DM, Syder AJ, Panis M, Wolk B, Hatziioannou T, McKeating JA, Bieniasz PD and Rice CM. Claudin-1 is a hepatitis C virus co-receptor required for a late step in entry. 2007. Nature, in press.